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Government estimates of the number of people trafficked into the United States each year have ranged from 14,500 to 50,000, with the most recent estimates on the lower end

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The main analysis will be supplemented with a multivariate linear regression to adjust for potential confounding variables (age, gender, baseline erosion area, periodontitis stage, baseline VAS score, smoking history, systemic medical history, and concomitant medications), and a repeated-measures mixed-effects model will assess the dynamic effect of the intervention

GHK has been shown to enhance extracellular matrix (ECM) activity in both dermal and pulmonary fibroblasts