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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Otwinowski Z., Minor W

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

10.1111/j.1600-079X.2008.00652.x J

These experiments confirmed that cagrilintide is a potent dual agonist, activating both receptor types, which is crucial for its therapeutic effect on reducing food intake and body weight, as demonstrated in preclinical rat models