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10.17219/acem/61914 175 ShishidoH.KishimotoY.KawaiN.ToyotaY.UenoM.KubotaT.et al

However, a growing body of evidence reveals a pronounced immunoinflammatory phenotype in OA, wherein macrophages, T/B lymphocytes, and inflammatory factors such as IL-1, TNF-, and IL-6 play a critical role in the local microenvironment ( 4.1 The role of immune cells in the local microenvironment of OA Macrophages are among the most prominent immune cells within the OA synovium

Exogenous taurine supplementation however, has shown some promising results on increasing time to fatigue during exhaustive exercise by up to 50% in rodents, and time to VO 2max in men [7981]