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Li, X., Yao, Y., Wu, F

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For instance, berberine inhibits endothelial ferroptosis and AS by suppressing ACSL4 expression ( 4.1.2 System Xc -/GSH/GPX4 pathway Ferroptosis is mainly induced by inhibiting glutathione production, with the System Xc -/GSH/GPX4 pathway playing a key role in preventing LPO

Therefore it can be concluded that black berry administration could minimize the toxic effects of fluoride indicating its free radical-scavenging and potent anti-oxidant activities