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The benefits rely on maintaining high concentrations in the muscle, so consistent, long-term use is generally considered safe and effective

Instead, their therapeutic benefits are mainly brought about by the release of paracrine factors [28, 45, 46]

Adv Nutr (2019) 10(Suppl1):S49S66

Before making treatment recommendations, providers review: This evaluation helps ensure that treatment decisions are individualized and medically appropriate