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Heffernan 2001a Mouse studies using chronic osmotic pump delivery showed AOD-9604 increased fat oxidation and plasma glycerol (a lipolysis marker) to a degree comparable with full-length hGH, without inducing hyperglycaemia or reducing insulin secretion

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To overcome these challenges, future studies should focus on developing advanced imaging techniques, such as MRI, to track the real time biodistribution of MNPs (Remmo et al., 2024)