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Epithalon, Melatonin, and Circadian Regulation Because Epithalon is associated with pineal and circadian research, its impact on melatonin-related pathways has received particular attention: Rat studies suggest that Epithalon may influence both synthesis and release of melatonin by modulating AANAT and pCREB-related transcription factors, which play central roles in the melatonin production pathway

But they are marketed and used for many other purposes, which could be permitted off-label if the drugs were cleared

Dihexa is now scheduled for PCAC review before the end of February 2027, alongside four other peptides: LL-37, GHK-Cu, PEG-MGF, and Melanotan II

It is not approved for human therapeutic use in Australia and is not for human or animal consumption