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In this article, we summarize the anticancer properties of quercetin against gastrointestinal (GI) cancers in vivo and in vitro and also assess its possible inhibitory effect on human cancers based on its cellular and molecular mechanisms

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Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]

Evaluates new medical technologies: NICE assesses the clinical and cost-effectiveness of new medical technologies, such as drugs and medical devices, to determine whether they should be made available on the NHS