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Through targeting mechanisms such as antigen loss, T-cell exhaustion, and immunosuppressive TME remodeling, tumors not only achieve immune evasion but also critically impair the formation of durable memory T-cell responses, which are essential for long-term protection

For instance, SLC38A1-mediated glutamine uptake promotes ferroptosis and triggers heart injury in ischemia-reperfusion [14], while AMPK-mediated BECN1 phosphorylation promotes ferroptosis by directly blocking system X c activity

Bai X, Nie P, Lou Y, Zhu Y, Jiang S, Li B, Luo P

Because collagen is naturally found in food, its considered by most to be safe for breastfeeding