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Although therapeutic strategies targeting the immune-inflammatory response (e.g., corticosteroids and immunosuppressive drugs) are effective in non-PF interstitial lung disease, they have no discernible impact on the fibrotic process in PF [31]

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Another study reported the interplay between ROS and SIRT1 in cell death during EV71 infection, and inhibition of ROS by NAC was shown to reduce EV71 propagation 149

doi: 10.3389/fmed.2023.1124275 Received 14 December 2022 Accepted 27 February 2023 Published 22 March 2023 Volume 10 - 2023 Edited by Ana Sandoval-Rodriguez, University of Guadalajara, Mexico Reviewed by Angelo Armandi, University of Turin, Italy