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Significantly decreased mRNA expression of SOD1 was observed in the white adipose tissue of KK-A y mice compared to C57BL/6 control mice (Furukawa et al

Int J Radiat Oncol Biol Phys 82(5):1967-72, 2012

With the increasing focus of research on stress in plants that developed in the 1980s, ROS came to be seen as inevitable molecular thugs, a price that had to be paid for aerobic metabolism and that could best be met by careful policing via antioxidant systems