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A: These mechanisms can improve glucose control by enhancing glucose-dependent insulin secretion and reducing appetite and body weight

[12] Transaminases are cytosolic enzymes present in all cells, but are particularly abundant in the liver, kidney, intestine, and muscle

We argue that viewing MS through the lens of an early onset, slowly progressive cytodegeneration of white and gray matter elements, convolved with a variable overlay of adaptive autoimmunity, could readily explain the entire disease spectrum, and aligns well with emerging new evidence