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The pentose phosphate pathway, by generating NADPH, plays a crucial role in replenishing reduced glutathione levels, safeguarding the cell from oxidative damage and ensuring cellular survival and function

101 Wang Y, Lin W, Brown JE, Chen L, Pandak WM, Hylemon PB, et al

While there is a theoretical risk that CP antibodies could enhance disease via ADE, case reports in SARS-CoV and MERS-CoV outbreaks showed that CP therapy was safe and was associated with improved clinical outcomes 89,90