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Given the pH-responsive nature of borate ester bonds, we examined the degradation behavior of CSp-OxD hydrogels under varying pH conditions (pH = 5, 7, and 9)

In this study, Sprague-Dawley rats were administered with homocysteine neonatally from postnatal day 2 and then monitored until adulthood

, Fas ligand (FASLG), tumor necrosis factor (TNF), TNF superfamily member 10 (TNFSF10, also known as TRAIL)) binding their respective receptors, which recruit the adaptor protein Fas associated via death domain (FADD), forming the death-inducing signaling complex (DISC)