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Interleukin-6 (IL-6) and IL-10 levels, particularly their ratio, were found to accurately predict disease severity (11)

depletion of AS-IL6 suppresses the invasive phenotype, which can be rescued by exogenous IL-6 (Wang et al., 2016)

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FIGURE 2 3.2 GHK-Cu inhibited the expression of inflammatory cytokines in DSS-induced colitis mice Figures 3AD show that Western blot analysis detected marked elevations in IL-1, IL-6, and TNF- levels in colonic tissue of DSS-induced colitis mice, indicating a robust inflammatory response