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Trouble in the Gut Is Trouble in the Brain Gut Pathogens Interaction With the Brain Is Multipronged Besides low levels of oxygen and hydrogen sulfide, and high levels of fatty acids, a healthy gut requires the proper regulation of immunity, hormones, gut-blood permeability, bowel movements, and stomach-acid and bile secretion

More recent research found that lactate can act as a viable energy source and increase in the brain during neuronal activity, suggesting that it may replace glucose as the primary energy source for neurons (Wyss et al., 2011)

Treatment with 4-hydroxytamoxifen (4-OHT) activates ER:RAS, inducing senescence (Supplementary Fig

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