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Low-density lipoprotein receptor-related protein 1 as a potential therapeutic target in Alzheimer's disease

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Oral dosing studies have used comparable per-kilogram doses with demonstrable efficacy

Studies have suggested that Nrf2 is activated in the joints of arthritic mice and patients with rheumatoid arthritis, whereas Nrf2 deficiency is associated with accelerated arthritis development 44,45 , suggesting that Nrf2 might be a potential therapeutic target for OA