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Concurrently, protein arginine methylation, a post-translational modification facilitated by the family of protein arginine methyltransferases, has been recognized as an essential regulator of cellular functions in multiple organs [11, 12]

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30 , who showed that the mTOR inhibitor, Torin, inhibited ATF4-sensitive genes through a mechanism that was independent of eIF2 phosphorylation and involved mTOR-dependent stabilization of ATF4 by eIF4E-BP1