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To investigate the effect of curcumin on HO-1, PSCs were treated with curcumin (1, 5, 10 or 20 M) for 6, 9, 12 or 24 h

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Keywords Carbon monoxide (CO) Source: a colorless, odorless gas produced by incomplete combustion of organic compounds most fatalities result from fires, stoves, portable heaters, however automobile exhaust cause approximately one third of deaths (these often are associated with malfunctioning or obstructed exhaust systems and suicide attempts) cigarette smoke is a significant source of CO natural gas contains no CO, but improperly vented gas water heaters, furnaces, kerosene space heaters, charcoal grills, hibachis, and Sterno stoves all emit CO Mechanism of Action: CO toxicity causes impaired oxygen delivery and utilization at the cellular level CO affects several different sites within the body but has its most profound impact on the organs with the highest oxygen requirement (eg, brain, heart)