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Intestinal macrophages from individual with Crohns disease have reduced selenoprotein expression Utilizing published scRNAseq data from inflamed and non-inflamed colonic biopsies from individuals with CD and control biopsies from 71 donors, changes in macrophage populations and gene expression were assessed

Proposed mechanisms for the role of iron in neurodegeneration include increased oxidative stress, possibly due to enhanced generation of reactive oxygen species (ROS) associated with increased protein aggregation [26, 117]

M., Hsu J., Ferguson M., et al., A Brain Network for Deep Brain Stimulation Induced Cognitive Decline in Parkinson's Disease, Brain 145, no

It is that powerful because its by far the most abundant antioxidant produced by the human body