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Gerade bei chemischen Substanzen kommt es hufig auf Detailfragen an

The early effects of GSTO1 inhibition by C1-27 (4 h treatment) predominantly involved induction of several stress-response-associated genes ( OSGIN1 , HMOX1 , SLC7A11 , DNAJB9 and so on) (Supplementary Table 14)

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These neoplasms can be very aggressive but as they are lacking angiogenesis, it was immediately evident that anti-angiogenic treatment could have been completely ineffective in these patients and, for the first time, was suggested that this type of therapeutic approach could face resistance, as all the others do [5]