Igap 18:252266 Bandowe BAM, Frnkl L, Grosjean M, Tylmann W, Mosquera PV, Hampel H, Schneides T (2018) A 150-year record of polycyclic aromatic compound (PAC) deposition from high Andean Cajas National Park, southern Ecuador
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Biodistribution studies showed preferential accumulation in the olfactory bulb and cerebrospinal fluid, with spread to striatum and substantia nigra, consistent with absorption along olfactory/trigeminal pathways and transit across the cribriform plate into CSF (Fig
While long-term exposure increases the risk of lung diseases such as chronic obstructive pulmonary disease (COPD) and asthma, especially in adolescents, short-term exposure can cause airway inflammation, hyperreactivity, decreased pulmonary function, susceptibility to microbial infection, and exacerbation of existing lung diseases