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For instance, phosphorylated forms of thiamin, including thiamin diphosphate (TDP) and thiamin pyrophosphate (TPP), are required cofactors for enzymes of glycolysis, the citric acid cycle, and the pentose phosphate pathway (22)

GABA A receptors exist on medium spiny neurons (MSN) in the NAc, thus it is possible that modulation of DA sensitivity is enhanced by direct stimulation of GABA A receptors on MSN 83