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A recent randomized controlled trial has shown that probiotics stabilizes the mucosal immune function that in turn protects the MASLD patients from increased intestinal permeability (166)

Prospective hepatoprotective actions of novel nano-formulations of sildenafil and neem extract in counteracting oral carbon tetrachloride-induced liver injury in rats

Subsequent efforts to identify the enzyme responsible for cGAMP production led to the characterization of cyclic GMP-AMP synthase (cGAS), a cytosolic DNA sensor that directly binds double-stranded DNA and catalyzes cGAMP synthesis upon activation (Sun et al., 2013)

With the observation of the DNA damage, we proceeded to determine the impact on cell cycle progression