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Diabetic wound healing studies using collagen dressings with GHK demonstrated a 9-fold increase in collagen synthesis with better epithelialization and activation of fibroblasts and mast cells

The interaction between LAIR-1 and collagen, followed by signaling in CD8+ T cells, emphasizes its involvement in promoting T cell exhaustion and enhancing the expression of immune checkpoint molecules such as PD-1 and PD-L1, thereby facilitating the evasion of the immune system by tumors (107109)

doi: 10.1155/2014/151479

The establishment and the phenotypic characterization of VEGF transgenic mice have been previously reported (17)