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Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

This updated burden estimate is a decrease of 960 hours [(3,200 HOPDs 0.167 hours 2 quarters)(3,200 HOPDs 20 percent 0.167 hours 1 quarter)] at a savings of $52,858 (960 hours $55.06) for the CY 2027 reporting period, and a decrease of 2,027 hours [(3,200 HOPDs 20 percent 0.167 hours 3 quarters) + (3,200 HOPDs 80 percent 0.167 hours 4 quarters)] at a savings of $111,607 (2,027 hours $55.06/hour) annually beginning with the CY 2028 reporting period