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NF-B, a transcription factor that involved in inflammatory response, can be activated by hyperglycemic conditions, leading to RAAS activation, AGEs accumulation and nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidative stress

Biogenic amines are low molecular weight nitrogenous compounds with biological activity formed by the decarboxylation of specific amino acids, and a small amount is synthesized by animation and transamination reactions of aldehydes and ketones (Tsafack and Tsopmo, 2022)

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH

This method allows for rapid and efficient absorption, bypassing the digestive system and delivering essential nutrients directly to the cells