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Other studies in adults have also shown that smoking has a negative impact on the postoperative outcome of nasosinusal endoscopic surgery when assessed under the viewpoint of symptoms, quality of life scores, endoscopic analysis and CT-scan findings.32,33,34 In the pediatric population, Kim et al.35, retrospectively assessed 97 patients submitted to paranasal sinuses surgery, and showed that children exposed to cigarette smoke had a worse postoperative outcome based on endoscopic analysis

A 2015 review of 28 studies (2,454 participants) of cannabinoids in which chronic pain was assessed found the studies generally showed improvements in pain measures in people taking cannabinoids, but these did not reach statistical significance in most of the studies

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